Brain wave study hints at new Drug's potential
NCT ID NCT05049343
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage study tested a drug called SAGE-904 in 22 healthy volunteers to see how it changes brain activity after a ketamine challenge. Researchers measured brain waves using EEG to check if SAGE-904 alters responses to sounds. The goal was to understand how the drug works in the brain, not to treat any disease.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
SAGE-904
What this could lead to
If successful, this study could help researchers understand how SAGE-904 affects brain activity, potentially guiding future studies for conditions like depression or schizophrenia.
What could go wrong
This is a very early Phase 1 study in only 22 healthy people, not patients. It measures brain signals, not symptoms, so even positive results may not lead to a treatment.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sage Investigational Site
Newark, New Jersey, 07103, United States