Could less radiation be better for brain cancer?

NCT ID NCT05781321

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tests whether a shorter, higher-dose radiation treatment works as well as the standard longer course for people with glioblastoma, an aggressive brain cancer. About 170 adults with confirmed glioblastoma will receive either short or standard radiation. The goal is to see if the shorter schedule can control the tumor and improve survival while possibly causing fewer side effects.

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Contacts and locations

Locations

  • Mayo Clinic Health System in Albert Lea

    Albert Lea, Minnesota, 56007, United States

  • Mayo Clinic Health System-Eau Claire

    Eau Claire, Wisconsin, 54701, United States

  • Mayo Clinic Health System-Franciscan Healthcare

    La Crosse, Wisconsin, 54601, United States

  • Mayo Clinic Health Systems-Mankato

    Mankato, Minnesota, 56001, United States

  • Mayo Clinic Radiation Therapy - Northfield

    Northfield, Minnesota, 55057, United States

  • Mayo Clinic in Arizona

    Scottsdale, Arizona, 85259, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.