New study tracks safety of NF1 drug selumetinib in kids

NCT ID NCT05388370

First seen Mar 16, 2026 · Last updated May 22, 2026 · Updated 10 times

Summary

This study monitors the safety of selumetinib in children aged 3 to 18 with neurofibromatosis type 1 (NF1) who have symptomatic, inoperable tumors. Researchers will track heart function, bone growth, muscle enzymes, liver health, eye problems, and puberty development over time. The goal is to better understand real-world risks and long-term effects in routine medical care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEUROFIBROMATOSIS TYPE 1 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Research Site

    Vienna, Austria

  • Research Site

    Amiens, France

  • Research Site

    Angers, France

  • Research Site

    Bordeaux, France

  • Research Site

    Lille, France

  • Research Site

    Lyon, France

  • Research Site

    Marseille, France

  • Research Site

    Paris, France

  • Research Site

    Rennes, France

  • Research Site

    Strasbourg, France

  • Research Site

    Toulouse, France

  • Research Site

    Tours, France

  • Research Site

    Vandœuvre-lès-Nancy, France

  • Research Site

    Villejuif, France

  • Research Site

    Dresden, Germany

  • Research Site

    Duisburg, Germany

  • Research Site

    Hamburg, Germany

  • Research Site

    Hanover, Germany

  • Research Site

    München, Germany

  • Research Site

    Tübingen, Germany

  • Research Site

    Petah Tikva, Israel

  • Research Site

    Ramat Gan, Israel

  • Research Site

    Tel Aviv, Israel

  • Research Site

    Florence, Italy

  • Research Site

    Genova, Italy

  • Research Site

    Milan, Italy

  • Research Site

    Padova, Italy

  • Research Site

    Pavia, Italy

  • Research Site

    Roma, Italy

  • Research Site

    Torino, Italy

  • Research Site

    Trieste, Italy

  • Research Site

    Rotterdam, Netherlands

  • Research Site

    Lisbon, Portugal

  • Research Site

    Porto, Portugal

  • Research Site

    Barcelona, Spain

  • Research Site

    Madrid, Spain

  • Research Site

    Málaga, Spain

  • Research Site

    Santiago de Compostela, Spain

  • Research Site

    Seville, Spain

  • Research Site

    Basel, Switzerland

  • Research Site

    Bern, Switzerland

  • Research Site

    Lausanne, Switzerland

  • Research Site

    Sankt Gallen, Switzerland

  • Research Site

    London, United Kingdom

  • Research Site

    Manchester, United Kingdom

  • Research Site

    Newcastle upon Tyne, United Kingdom

Conditions

Explore the condition pages connected to this study.