New shot aims to tame sickle cell pain
NCT ID NCT07224360
First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times
Summary
This study tests a new drug called anumigilimab in 63 adults with sickle cell disease to see if it is safe. Participants get weekly injections for 64 weeks, starting with a low dose that increases to their personal maximum. The goal is to reduce painful crises, but people will still need ongoing care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AOUI Verona and University of Verona
RECRUITINGVerona, 37134, Italy
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Arthur M. Blank Hospital- Children's Healthcare of Atlanta
RECRUITINGAtlanta, Georgia, 30329, United States
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CHU Saint-Pierre
RECRUITINGBrussels, 1000, Belgium
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CHU de Nantes, Hotel-Dieu
RECRUITINGNantes, 44093, France
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Center for Cancer and Blood Disorders
RECRUITINGBethesda, Maryland, 20817, United States
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Central Middlesex Hospital
RECRUITINGLondon, NW10 7NS, United Kingdom
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Hammersmith Hospital Imperial College Healthcare NHS Trust
RECRUITINGLondon, W120HS, United Kingdom
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Institut Universitaire du Cancer de Toulouse
RECRUITINGToulou, 31100, France
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Jacobi Medical Center
RECRUITINGThe Bronx, New York, 10461, United States
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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Southern Specialty Research
RECRUITINGFlowood, Mississippi, 39232, United States
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St George's University Hopsitals NHS Foundation Trust
RECRUITINGLondon, SW17 0QT, United Kingdom
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The Foundation for Sickle Cell Disease
RECRUITINGHollywood, Florida, 33023-6703, United States
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UAMS Medical Center
RECRUITINGLittle Rock, Arkansas, 72202, United States
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University of California Irvine
RECRUITINGOrange, California, 92868, United States
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Virginia Commonwealth University
RECRUITINGRichmond, Virginia, 23298, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Co-Designed support help parents embrace sickle cell care?
- Can community hospitals in zambia master severe disease care?
- A Pocket-Sized coach for sickle cell: can an app turn Pill-Taking into a habit?
- Can a phone app keep teens on track with sickle cell treatment?
- A common amino acid may calm sickle cell pain crises — a trial puts it to the test
- A drug that protects the liver may make stem cell transplants safer for children with sickle cell disease