New probiotic passes first safety test in small human study

NCT ID NCT06380270

Completed Symptom relief Sponsor: Liaquat University of Medical & Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study tested whether an oral probiotic called Streptococcus salivarius eK12 is safe and well-tolerated in healthy adults. Researchers gave 29 participants either the probiotic or a placebo and monitored for side effects, changes in vital signs, and blood test results. The goal was to see if this probiotic could eventually be used to support oral health and prevent infections like strep throat.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Oral probiotic Streptococcus salivarius eK12 (Bactoblis® Evol)
What this could lead to: If successful, this could confirm that the probiotic is safe for people, paving the way for larger studies on preventing strep throat or improving oral hygiene.
What could go wrong: This is a small, early-stage safety study with only 29 participants, so it cannot prove the probiotic works for any condition. Side effects like stomach upset are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SAFETY TOLERABILITY

Contacts and locations

Locations

Jam Ghulam Qadir Civil Hospital

Hub, 90250, Pakistan

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