New probiotic passes first safety test in small human study
NCT ID NCT06380270
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study tested whether an oral probiotic called Streptococcus salivarius eK12 is safe and well-tolerated in healthy adults. Researchers gave 29 participants either the probiotic or a placebo and monitored for side effects, changes in vital signs, and blood test results. The goal was to see if this probiotic could eventually be used to support oral health and prevent infections like strep throat.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oral probiotic Streptococcus salivarius eK12 (Bactoblis® Evol)
What this could lead to
If successful, this could confirm that the probiotic is safe for people, paving the way for larger studies on preventing strep throat or improving oral hygiene.
What could go wrong
This is a small, early-stage safety study with only 29 participants, so it cannot prove the probiotic works for any condition. Side effects like stomach upset are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Jam Ghulam Qadir Civil Hospital
Hub, 90250, Pakistan