Could a hormone and a sleep aid prevent brain surgery in preemies?

NCT ID NCT05617833

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests whether giving two medicines—erythropoietin and melatonin—together is safe for very premature babies who have bleeding in the brain. About 60 infants will receive either the drug combination or a placebo, along with standard care, to see if the treatment causes serious side effects. If safe, future studies will check if this approach can prevent the need for lifelong brain shunts.

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The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins All Children's Hospital

    RECRUITING

    St. Petersburg, Florida, 33701, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Email: •••••@•••••

    Contact