A nerve block in the lower back may ease pain during scarless gynecologic surgery — a trial puts it to the test
NCT ID NCT07732322
First seen Jul 28, 2026 · Last updated Jul 30, 2026 · Updated 2 times
Summary
This trial tests whether adding a sacral erector spinae plane (ESP) block — a local anesthetic injection near the lower spine — to general anesthesia can reduce pain and opioid use during and after vNOTES, a minimally invasive gynecologic surgery that uses the vagina as a natural opening. The study will compare two groups of adults undergoing elective vNOTES: one receiving general anesthesia alone and one receiving general anesthesia plus the block. Researchers will measure intraoperative opioid consumption, postoperative pain scores, and the amount of additional pain medication needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a sacral erector spinae plane (ESP) block — a local anesthetic injection near the lower spine
- What this could lead to
- If effective, this nerve block could offer a way to manage pain during vNOTES surgery while reducing the need for strong opioids.
- What could go wrong
- This is a small, early-stage trial with only 42 participants, so results may not apply broadly. Nerve blocks carry risks such as infection, bleeding, or allergic reaction.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
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