New hope for rare ovarian cancer: drug shrinks tumors after immunotherapy fails

NCT ID NCT07168083

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study tests a drug called sacituzumab in 22 people with a rare and aggressive type of ovarian cancer (clear cell carcinoma) that has worsened after immunotherapy. The drug is an antibody-drug conjugate designed to target and kill cancer cells. The main goal is to see how many patients have their tumors shrink by at least 30%.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
sacituzumab (SKB264)
What this could lead to
If it works, this could offer a new treatment option for a rare and aggressive ovarian cancer that has stopped responding to immunotherapy.
What could go wrong
This is a small, early-stage study with only 22 participants. The drug may not work for everyone, and side effects are possible. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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