New combo therapy shows promise for Tough-to-Treat breast cancer
NCT ID NCT04448886
First seen Jan 18, 2026 · Last updated May 15, 2026 · Updated 19 times
Summary
This study tests whether adding pembrolizumab (Keytruda) to sacituzumab govitecan helps people with a certain type of advanced breast cancer (HR+/HER2-) live longer without the disease getting worse. About 110 participants will receive either the drug alone or the combination. The goal is to see if the combo improves outcomes compared to the single drug.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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DF/BWCC in Clinical Affiliation with South Shore Hospital
South Weymouth, Massachusetts, 02190, United States
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DFCI @ Foxborough
Foxborough, Massachusetts, 02035, United States
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DFCI @ Milford Regional Hospital
Milford, Massachusetts, 01757, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Emory University/Winship Cancer Institute
Atlanta, Georgia, 30322, United States
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University of Chicago Medical Center
Chicago, Illinois, 60637, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27599, United States
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University of Pennsylvania-Abramson Cancer Center
Philadelphia, Pennsylvania, 19104, United States
Conditions
Explore the condition pages connected to this study.