New drug could delay type 1 diabetes progression

NCT ID NCT07187531

Recruiting now Disease control Sponsor: SAb Biotherapeutics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests a new drug called SAB-142 in people recently diagnosed with type 1 diabetes. The goal is to see if it can help the body keep making its own insulin for longer, slowing the disease. About 159 people aged 5 to 40 will receive either the drug or a placebo, and researchers will monitor side effects and blood sugar control over 12 months.

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Conditions

The condition(s) this trial relates to.

type 1 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TYPE 1 DIABETES

Contacts and locations

Locations

Alder Hey Children's NHS Foundation Trust
RECRUITING

Liverpool, L12 2AP, United Kingdom
Aotearoa Clinical Trials
RECRUITING

Auckland, Auckland, 1640, New Zealand
Asheville Clinical Research
RECRUITING

Asheville, North Carolina, 28803, United States
Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Universitaire Robert-Debre
RECRUITING

Paris, 75019, France
Azienda Ospedaliera Universitaria Integrata Verona-Ospedale della Donna e del Bambino_Borgo Trento
RECRUITING

Verona, 37126, Italy
Azienda Ospedaliero Universitaria Maggiore della Carità di Novara
RECRUITING

Turin, 28100, Italy
Barts Health NHS Trust - The Royal London Hospital
RECRUITING

London, E1 1BB, United Kingdom
Benaroya Research Institute at Virginia Mason
RECRUITING

Seattle, Washington, 98101, United States
Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital
RECRUITING

Cambridge, CB2 0QQ, United Kingdom
Children's Healthcare of Atlanta (CHOA) - Center for Advanced Pediatrics
RECRUITING

Atlanta, Georgia, 30329, United States
Children's Medical Centre Dallas
NOT_YET_RECRUITING

Dallas, Texas, 75235, United States
Children's Mercy Hospital Kansas City - Pediatric Care Clinic
RECRUITING

Kansas City, Missouri, 64111, United States
Cook Children's Medical Center
NOT_YET_RECRUITING

Fort Worth, Texas, 76104, United States
Dunedin Hospital
RECRUITING

Dunedin, 9016, New Zealand
Government of Western Australia - Child and Adolescent Health Service - Perth Children's Hospital
RECRUITING

Nedlands, 6009, Australia
Groupe sante CHC - Clinique du MontLegia
RECRUITING

Liège, 4000, Belgium
Hannoversche Kinderheilanstalt
RECRUITING

Hanover, 30173, Germany
Harvard Medical School - Joslin Diabetes Center and Joslin Clinical (JDS)
NOT_YET_RECRUITING

Boston, Massachusetts, 02215, United States
Helsingin Yliopistollinen Keskussairaala
NOT_YET_RECRUITING

Helsinki, 00029, Finland
Hospital Universitario Virgen Macarena
RECRUITING

Seville, 41009, Spain
Hospital Universitario Virgen de la Victoria
NOT_YET_RECRUITING

Málaga, 29010, Spain
Hospital de Cruces
RECRUITING

Barakaldo, 48903, Spain
Hospital of Lithuanian University of Health Sciences Kauno Klinikos
RECRUITING

Kaunas, 50161, Lithuania
IRCCS Ospedale San Raffaele
RECRUITING

Milan, 20132, Italy
IUH - Riley Hospital for Children - Riley Outpatient Center - Pediatric Diabetes & Endocrinology
NOT_YET_RECRUITING

Indianapolis, Indiana, 46202, United States
Instytut Diabetologii
RECRUITING

Warsaw, 02-117, Poland
Klinikum Augsburg
NOT_YET_RECRUITING

Augsburg, 86156, Germany
MTZ Clinical Research Sp. z o.o.
RECRUITING

Warsaw, 02-172, Poland
Mary Bridge Children's Outpatient Center - Tacoma
RECRUITING

Tacoma, Washington, 98405-3720, United States
Medizinische Universitaet Graz - Klinik fuer Innere Medizin
RECRUITING

Graz, 8036, Austria
Medizinische Universitaet Graz - Universitaetsklinik fuer Kinder und Jugendheilkunde
RECRUITING

Vienna, 1090, Austria
Medizinische Universitaet Wien - Universitaetsklinik fuer Kinder und Jugendheilkunde
NOT_YET_RECRUITING

Vienna, 1090, Austria
Medizinische Universität Innsbruck
NOT_YET_RECRUITING

Innsbruck, 6020, Austria
N.C. Children's Hospital - Children's Specialty Clinics - Chapel Hill at Carolina Pointe II
RECRUITING

Chapel Hill, North Carolina, 27514, United States
NHS Lothian - Royal Hospital for Sick Children
NOT_YET_RECRUITING

Edinburgh, EH9 1LF, United Kingdom
New Zealand Clinical Research - Christchurch
RECRUITING

Christchurch, 8011, New Zealand
Noahs Ark Childrens Hospital for Wales
RECRUITING

Cardiff, CF14 4XW, United Kingdom
Nottingham University Hospitals NHS Trust - Queen's Medical Centre (QMC)
RECRUITING

Nottingham, NG7 2UH, United Kingdom
Oxford University Hospitals NHS Trust - John Radcliffe Hospital
NOT_YET_RECRUITING

Oxford, OX3 9DU, United Kingdom
Queensland Children's Hospital
RECRUITING

Brisbane, 4101, Australia
Royal North Shore Hospital (RNSH)
RECRUITING

St Leonards, 2065, Australia
SZPITAL KLINICZNY im. Karola Jonschera - UNIWERSYTETU MEDYCZNEGO im. Karola Marcinkowskiego
NOT_YET_RECRUITING

Poznan, 60-572, Poland
San Antonio Clinical Trials
RECRUITING

San Antonio, Texas, 78240, United States
San Jose Clinical Trials, LLC
RECRUITING

San Jose, California, 95128, United States
Sanford Medical Center Fargo
RECRUITING

Fargo, North Dakota, 58104, United States
Steno Diabetes Center
RECRUITING

Herlev, 2730, Denmark
Technische Universität Munich
RECRUITING

Oberschleißheim, 85764, Germany
Texas Children's Hospital - Clinical Care Center - Pediatric Renal Clinic
RECRUITING

Houston, Texas, 77030, United States
The Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
The Royal Children's Hospital Melbourne
NOT_YET_RECRUITING

Parkville, 3052, Australia
The Royal Melbourne Hospital (RMH)
RECRUITING

Parkville, 3052, Australia
Turun Yliopistollinen Keskussairaala (TYKS)
RECRUITING

Turku, 20521, Finland
UPMC Children's Hospital of Pittsburgh
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15224, United States
UZ Leuven
RECRUITING

Leuven, 3000, Belgium
Universitair Ziekenhuis Brussel
RECRUITING

Jette, 1090, Belgium
Universite Paris Descartes - Institut Cochin
RECRUITING

Paris, 75014, France
University Children's Hospital Ljubljana (UCHL)
RECRUITING

Ljubljana, 1525, Slovenia
University College London Hospitals NHS Foundation Trust - University College Hospital
RECRUITING

London, NW1 2PG, United Kingdom
University at Buffalo MD Physicians Group
RECRUITING

Buffalo, New York, 14203, United States
University of California San Francisco Benioff Children's Hospital
RECRUITING

San Francisco, California, 94158, United States
University of Colorado - Barbara Davis Center for Diabetes
RECRUITING

Aurora, Colorado, 80045, United States
University of Florida College of Medicine
RECRUITING

Gainesville, Florida, 32610, United States
University of Miami - Gables One Tower
RECRUITING

Miami, Florida, 33136, United States
University of New Mexico Hospital
NOT_YET_RECRUITING

Albuquerque, New Mexico, 87106, United States
University of Virginia Health System - Pediatric Diabetes Clinic
NOT_YET_RECRUITING

Charlottesville, Virginia, 22903, United States
Uniwersytecki Szital Klniczny w Opolu
NOT_YET_RECRUITING

Opole, 46-020, Poland
Waikato Hospital
RECRUITING

Hamilton, 3204, New Zealand
Waitemata District Health Board- North Shore Hospital
RECRUITING

Auckland, 0620, New Zealand
Warszawski Uniwersytet Medyczny - Klinika Pediatrii
NOT_YET_RECRUITING

Warsaw, 02-091, Poland
Wellington Regional Hospital
NOT_YET_RECRUITING

Wellington, 6021, New Zealand
Westmead Hospital
RECRUITING

Westmead, 2145, Australia

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