Could a quick artery fix replace daily pills for this blood pressure condition?

NCT ID NCT07328230

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a procedure called superselective adrenal artery embolization (SAAE) against the standard pill spironolactone for people with idiopathic hyperaldosteronism, a condition that causes high blood pressure. About 172 participants will be randomly assigned to either the procedure or the medication. The goal is to see if SAAE can safely and effectively lower blood pressure, potentially offering a one-time alternative to daily drugs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
spironolactone
What this could lead to
If SAAE works well, it could offer a one-time procedure to control blood pressure instead of taking daily medication.
What could go wrong
This is a mid-stage trial with 172 people, so results may not apply to everyone. The procedure carries risks like bleeding or damage to the adrenal gland.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College

    RECRUITING

    Beijing, Beijing Municipality, 100037, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Second Affiliated Hospital of Nanchang University

    RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Chengdu Medical College

    RECRUITING

    Chengdu, Sichuan, 610500, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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