New pill shows promise for controlling blood pressure in rare hormone disorder

NCT ID NCT04605549

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called CIN-107 in 15 adults with primary aldosteronism, a condition where the body makes too much of a hormone that raises blood pressure. Participants took the drug once daily for up to 12 weeks to see if it safely lowered blood pressure. The goal was to find a better way to manage this condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CIN-107 (a drug taken as a tablet once daily)

What this could lead to

If it works, this could provide a new treatment option for people with primary aldosteronism to better control their blood pressure.

What could go wrong

This was a small, early-phase study with only 15 participants, so results may not apply to everyone. The drug may cause side effects or not work as well in larger, longer trials.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperaldosteronism primary aldosteronism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Greenbrae, California, 94904, United States

  • Research Site

    San Francisco, California, 94110, United States

  • Research Site

    West Hollywood, California, 90048, United States

  • Research Site

    Chicago, Illinois, 60611, United States

  • Research Site

    Baltimore, Maryland, 21287, United States

  • Research Site

    Ann Arbor, Michigan, 48109, United States

  • Research Site

    Rochester, Minnesota, 55905, United States

  • Research Site

    Cincinnati, Ohio, 45245, United States

  • Research Site

    Columbus, Ohio, 43210, United States

  • Research Site

    Dallas, Texas, 75390-9047, United States