Real-World study checks how oral semaglutide works for diabetes
NCT ID NCT05230615
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study looked at how once-daily oral semaglutide (Rybelsus) affects blood sugar and body weight in adults with type 2 diabetes in Italy. Researchers followed 458 patients for about 8-10 months as they took the medication as part of their normal care. The goal was to see if the drug helps lower blood sugar levels in everyday practice.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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IRCCS MultiMedica
Sesto San Giovanni, Italy
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Master Centre for Italy
Rome, 00144, Italy
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
oral semaglutide (Rybelsus)
What this could lead to
If successful, this study could confirm that oral semaglutide helps control blood sugar and weight in real-world settings, supporting its use for type 2 diabetes management.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by other factors. It is also completed, so findings are already known and may not lead to new treatments.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.