New drug combo aims to prevent deadly transplant complications in leukemia patients

NCT ID NCT07548983

First seen Apr 28, 2026 · Last updated May 21, 2026 · Updated 4 times

Summary

This early-phase trial tests whether giving ruxolitinib followed by ruxolitinib plus azacitidine after a stem cell transplant can safely prevent graft-versus-host disease (GVHD) and keep acute myeloid leukemia (AML) from coming back. About 40 adults with AML in remission will take part. The study focuses on finding the best dose and checking for side effects.

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Contacts and locations

Locations

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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