New drug aims to cut blood removal in rare cancer
NCT ID NCT07648030
First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 4 times
Summary
This trial tests rusfertide, an injected drug, in Japanese adults with polycythemia vera, a rare blood cancer that causes too many red blood cells. The goal is to see if rusfertide can keep red blood cell levels under control and reduce the need for phlebotomy (blood removal). All participants receive rusfertide, and the study tracks their response over about 52 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- rusfertide
- What this could lead to
- If successful, rusfertide could offer a way to manage polycythemia vera with fewer blood removal procedures.
- What could go wrong
- This is a small, early-phase study with only 9 participants, so results may not apply broadly. The drug may not work as hoped or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Gunma University Hospital
NOT_YET_RECRUITINGMaebashi, Gunma, Japan
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Juntendo University Hospital
RECRUITINGBunkyo-ku, Tokyo, Japan
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Mie University Hospital
RECRUITINGTsu, Mie-ken, Japan
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Nagoya Medical Center
NOT_YET_RECRUITINGNagoya, Aichi-ken, Japan
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Tokyo Medical University Hospital
NOT_YET_RECRUITINGShinjuku-ku, Tokyo, Japan
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Tokyo Metropilitan Bokutoh Hospital
NOT_YET_RECRUITINGSumida-ku, Tokyo, Japan
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University of Miyazaki Hospital
NOT_YET_RECRUITINGMiyazaki, Japan
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University of Osaka Hospital
RECRUITINGSuita, Osaka, Japan
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University of Yamanashi Hospital
RECRUITINGChūō, Yamanashi, Japan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a hormone mimic curb the need for bloodletting in a blood cancer?
- Can a Dual-Action pill tame bone marrow tumors?
- Can a new drug reduce bloodletting for polycythemia vera?
- A simple Note-Taking change could transform blood cancer care
- Can a new drug help when standard treatment fails for polycythemia vera?
- New drug candidate targets Hard-to-Treat blood cancers