Lung cancer maintenance combo shows promise but study halted early

NCT ID NCT03559049

First seen Feb 17, 2026 · Last updated Apr 23, 2026 · Updated 9 times

Summary

This study tested a combination of two drugs (rucaparib and pembrolizumab) as maintenance therapy for people with stage IV non-small cell lung cancer. The goal was to see if this combination could delay cancer progression after initial treatment. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • The University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.