Shocking the nose back to life: new combo therapy for Parkinson's smell loss

NCT ID NCT07666477

Completed Symptom relief Sponsor: Mustafa Baran Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether combining a non-invasive brain stimulation technique (rTMS) with daily smell training could help people with Parkinson's disease recover their sense of smell and taste. 120 participants were split into four groups to compare the combo therapy against each treatment alone or a sham. The goal was to see if the combined approach leads to better sensory recovery, measured by standard smell tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS) and structured olfactory training
What this could lead to: If it works, this could offer a non-drug way to help people with Parkinson's regain their sense of smell and taste, improving daily life.
What could go wrong: This is a small, completed trial. The results may not apply to everyone, and the improvements might be modest or not last long. rTMS can cause mild side effects like headache or scalp discomfort.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OLFACTORY DYSFUNCTION PARKINSON DISEASE (PD)

Contacts and locations

Locations

Batman University

Batman, Batman, 72060, Turkey (Türkiye)

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