Heart shield: statin may guard against chemo damage in breast cancer
NCT ID NCT07254221
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking rosuvastatin, a cholesterol-lowering drug, can prevent heart damage caused by anthracycline chemotherapy in women with breast cancer. Four hundred participants will receive either rosuvastatin or a placebo daily for 12 months. The main goal is to see if the drug helps maintain heart pumping function and reduces signs of heart stress.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
rosuvastatin
What this could lead to
If it works, this could offer a simple way to protect the heart during breast cancer chemotherapy, reducing long-term heart risks.
What could go wrong
This is a Phase 4 trial, but it hasn't started yet. The benefit may be small or not apply to all patients, and statins can cause muscle pain or liver issues.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Kowsar Hospital, Fars Heart Foundation
Shiraz, Fars, Iran
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Modarres Hospital, Shahid Beheshti University of Medical Sciences
Tehran, Tehran Province, Iran
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Motahari Breast Cancer Clinic
Shiraz, Fars, 71344-1864, Iran
Contact Email: •••••@•••••
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Rajaee Hospital, Iran University of Medical Sciences
Tehran, Tehran Province, Iran
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sina Hospital, Tehran University of Medical Sciences
Tehran, Tehran Province, Iran
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Taleghani Hospital, Shahid Beheshti University of Medical Sciences
Tehran, Tehran Province, Iran
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Toba Oncology Department, Mazandaran University of Medical Sciences
Sari, Mazandaran, Iran
Contact Phone: •••-•••-•••• Email: •••••@•••••