Light-Activated dye could save sight from severe eye infections
NCT ID NCT06271772
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a light-activated dye called rose Bengal, combined with antibiotics and steroids, can improve vision in people with severe bacterial eye infections. About 60 adults with corneal ulcers and vision loss will receive either the dye treatment or a sham procedure. The goal is to see if the dye helps reduce scarring and leads to better eyesight after six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Rose Bengal (a dye) activated by green light, plus antibiotic and steroid eye drops
- What this could lead to
- If it works, this could offer a new way to treat severe bacterial eye infections, potentially improving vision and reducing scarring.
- What could go wrong
- This is a small, early feasibility study with only 60 participants. The treatment adds complexity and may not provide significant benefit over standard care. Risks include eye irritation or worsening infection.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aravind Eye Care System
Madurai, Tamil Nadu, India
-
Federal University of São Paulo
São Paulo, Brazil
More trials for these conditions
Other studies related to the condition(s) this trial covers.