Could interferon be a hidden trigger of blood clot damage after transplant?
NCT ID NCT07705789
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This study investigates how interferon and complement proteins contribute to thrombotic microangiopathy (TMA), a serious condition involving small blood clots and organ damage that can occur after stem cell transplants. Researchers will measure interferon levels, complement activity, and VEGF-A in blood and urine samples from 40 adults, including transplant recipients with and without TMA. The goal is to clarify whether interferon, alongside complement, drives the blood vessel damage seen in TMA.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could identify interferon as a key driver of TMA, pointing toward new treatment targets for this serious complication.
- What could go wrong
- This is an observational study with a small sample of 40 people, so findings may not apply broadly and will need confirmation in larger trials.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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