New hope for iTTP patients: study tests treatment without invasive plasma exchange
NCT ID NCT06291025
First seen Feb 28, 2026 · Last updated May 14, 2026 · Updated 13 times
Summary
This study tests whether a simpler treatment for immune thrombotic thrombocytopenic purpura (iTTP) can work without the standard plasma exchange procedure. Instead, patients receive plasma infusions, immune-suppressing drugs, and a medication called caplacizumab. The goal is to see if this approach is as safe and effective as the current standard, reducing the burden of care. About 131 adults with iTTP will take part.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Ap-Hm La Conception
RECRUITINGMarseille, 13005, France
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Ap-Hp Pitie Salpetriere
NOT_YET_RECRUITINGParis, 75651, France
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Ap-Hp Saint Louis
RECRUITINGParis, 75010, France
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Ap-Hp St Antoine
RECRUITINGParis, 75571, France
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CH PAU
NOT_YET_RECRUITINGPau, 64046, France
Contact Email: •••••@•••••
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CHU NICE
RECRUITINGNice, 06200, France
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Ch Saint-Nazaire
NOT_YET_RECRUITINGSaint-Nazaire, 44606, France
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ch Valenciennes
RECRUITINGValenciennes, 59322, France
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Chru Besanon
RECRUITINGBesançon, 25030, France
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Chu Amiens
RECRUITINGAmiens, 80054, France
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Chu Angers
RECRUITINGAngers, 49933, France
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Chu Bobigny
RECRUITINGBobigny, 93000, France
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Chu Bordeaux
RECRUITINGBordeaux, 33076, France
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Chu Clermont-Ferrand
RECRUITINGClermont-Ferrand, 63003, France
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Chu Edouard Herriot
RECRUITINGLyon, 69003, France
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Chu Lille
RECRUITINGLille, 59037, France
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Chu Limoges
NOT_YET_RECRUITINGLimoges, 87042, France
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Chu Martinique
NOT_YET_RECRUITINGFort-de-France, 97261, Martinique
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Chu Montpellier
RECRUITINGMontpellier, 34295, France
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Chu Nancy
RECRUITINGNancy, 54500, France
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Chu Nantes
RECRUITINGNantes, 44093, France
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Chu Nimes
RECRUITINGNîmes, 30029, France
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Chu Reims
RECRUITINGReims, 51092, France
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Chu Reunion Sud
RECRUITINGSaint-Pierre, 97448, Reunion
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Chu Rouen
RECRUITINGRouen, 76031, France
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Chu Strasbourg
RECRUITINGStrasbourg, 67091, France
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Chu Toulouse
RECRUITINGToulouse, 31000, France
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Chu Tours
NOT_YET_RECRUITINGTours, 37044, France
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Hopital Jean Verdie
RECRUITINGBondy, 93140, France
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Reunion Nord
RECRUITINGSaint-Denis, 97400, Reunion
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Conditions
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