Scientists investigate why entrectinib fails in some lung cancer patients

NCT ID NCT07199959

First seen Oct 01, 2025 · Last updated Apr 25, 2026 · Updated 27 times

Summary

This study aims to understand why some lung cancers with a specific genetic change (ROS1 fusion) stop responding to the drug entrectinib. Researchers will analyze tumor or blood samples from 38 people who have already taken entrectinib as part of their regular care. The goal is to identify genetic changes that cause resistance, which may help improve future treatments.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fudan university shanghai cancer center

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

Conditions

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