Cure My Disease

Don't miss your cure!

 Log in / Sign up

Brittle bone kids: is romosozumab safe Long-Term?

NCT ID NCT07366086

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows children and teens with osteogenesis imperfecta (brittle bone disease) who previously received romosozumab in an earlier trial. Researchers will monitor 71 participants for side effects over time. The goal is to see if the drug is safe for long-term use in this young population.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
romosozumab
What this could lead to
If successful, this could confirm that romosozumab is safe for long-term use in children with brittle bone disease, potentially leading to a new treatment option.
What could go wrong
This is a follow-up safety study, not a test of effectiveness. It is small (71 participants) and only includes those who already tolerated the drug, so results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OSTEOGENESIS IMPERFECTA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

osteogenesis imperfecta

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOGENESIS IMPERFECTA

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Indiana University

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Okayama Saiseikai Outpatient Center Hospital

    RECRUITING

    Okayama, Okayama-ken, 700-0013, Japan

  • Universitaetsklinikum Koeln

    RECRUITING

    Cologne, 50937, Germany

  • Universitaetsklinikum Wuerzburg

    RECRUITING

    Würzburg, 97074, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.