New hope for Hard-to-Treat cancers: experimental drug targets RAS mutations
NCT ID NCT06884618
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 21 times
Summary
This early-stage study tests a new drug, RO7673396, in people with advanced solid tumors that have a RAS mutation. The goal is to find a safe dose and see if the drug can shrink tumors when used alone or with other cancer treatments. About 405 participants will take part in two stages: first to find the right dose, then to check how well it works in specific cancer types.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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City of Hope Comprehensive Cancer Center
RECRUITINGDuarte, California, 91010, United States
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Clinica Universidad de Navarra
RECRUITINGPamplona, Navarre, 31008, Spain
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Florida Cancer Specialists - Sarasota (North Catttlemen Rd)
RECRUITINGSarasota, Florida, 34232, United States
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, 201315, China
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Hubei Cancer Hospital
RECRUITINGWuhan, 430079, China
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030-3721, United States
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National Cancer Centre - 30 Hospital Blvd
RECRUITINGSingapore, 168583, Singapore
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National Cheng Kung University Hospital
RECRUITINGTainan, 70403, Taiwan
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National Taiwan University Hospital
RECRUITINGTaipei, 10002, Taiwan
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New Zealand Clinical Research - Auckland
RECRUITINGAuckland, 1010, New Zealand
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New Zealand Clinical Research - Christchurch
RECRUITINGChristchurch, 8011, New Zealand
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Peter MacCallum Cancer Center
RECRUITINGParkville, Victoria, 3052, Australia
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Prince of Wales Hospital
RECRUITINGHong Kong, Hong Kong
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Princess Margaret Hospital
RECRUITINGToronto, Ontario, M5G 2M9, Canada
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Rigshospitalet
RECRUITINGKøbenhavn Ø, 2100, Denmark
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Smilow Cancer Hospital at Yale New Haven
RECRUITINGNew Haven, Connecticut, 06519-1110, United States
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South Texas Accelerated Research Therapeutics (START)
RECRUITINGSan Antonio, Texas, 78229-4427, United States
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St Vincent's Hospital Sydney
RECRUITINGDarlinghurst, New South Wales, 2010, Australia
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Sun Yat-Sen University Cancer Center - Huangpu Campus
RECRUITINGGuangzhou, Guangdong, 510555, China
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Sun Yat-Sen University Cancer Center;Department of Thoracic Surgery
RECRUITINGGuangzhou, 510050, China
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University of Colorado - Anschutz Medical Campus - PPDS
RECRUITINGAurora, Colorado, 80045, United States
Conditions
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