Desperate hope: single patient gets custom RNA therapy for returning bone cancer
NCT ID NCT07560709
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study provided a single patient with recurrent osteosarcoma (a type of bone cancer) access to a personalized treatment made from their own tumor's genetic material. The therapy, called RNA-loaded lipid particles (RNA-LPs), was given intravenously to try to control the cancer. Because it was a one-patient expanded access program, it does not provide broad evidence of safety or effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
personalized RNA-loaded lipid particles (RNA-LPs)
What this could lead to
If it works, this could point toward a treatment for recurrent osteosarcoma that uses the patient's own tumor material to target cancer cells.
What could go wrong
This is a single-patient expanded access protocol, not a formal trial, so results may not apply to others. The treatment is experimental and may not slow disease progression.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Florida Health
Gainesville, Florida, 32608, United States