Gut bacteria therapy aims to tame immunotherapy side effect

NCT ID NCT05726396

First seen Oct 31, 2025 · Last updated May 08, 2026 · Updated 23 times

Summary

This study tested whether a treatment made from healthy gut bacteria (called restorative microbiota therapy) is safe and possible for people with severe colon inflammation caused by cancer immunotherapy. It was designed for patients whose colitis did not improve with steroids. The study was withdrawn before enrolling anyone, so no results are available.

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Contacts and locations

Locations

  • Essentia Health Cancer Center

    Duluth, Minnesota, 55805, United States

  • Essentia Health Deer River Clinic

    Deer River, Minnesota, 56636, United States

  • Essentia Health Fosston

    Fosston, Minnesota, 56542, United States

  • Essentia Health Hibbing Clinic

    Hibbing, Minnesota, 55746, United States

  • Essentia Health Sandstone

    Sandstone, Minnesota, 55072, United States

  • Essentia Health St. Joseph's Medical Center

    Brainerd, Minnesota, 56401, United States

  • Essentia Health St. Mary's Detroit Lakes Clinic

    Detroit Lakes, Minnesota, 56501, United States

  • Essentia Health Virginia Clinic

    Virginia, Minnesota, 55792, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55414, United States

Conditions

Explore the condition pages connected to this study.