New weekly shot hopes to tame genetic obesity
NCT ID NCT06239116
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 25 times
Summary
This study tests a new weekly injection called RM-718 in people with obesity, including those with a genetic condition affecting the MC4R pathway (like Prader-Willi syndrome). The main goal is to check the drug's safety and how the body processes it. About 150 participants will take part in this early-stage research.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ann and Robert H. Lurie Children's Hospital of Chicago (Part C and Part D)
RECRUITINGChicago, Illinois, 60611, United States
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Boston Children's Hospital (Part C only)
RECRUITINGBoston, Massachusetts, 021115, United States
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Brigham and Women's Hospital (Part C and Part D)
RECRUITINGBoston, Massachusetts, 02115, United States
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UAB Pediatric Endocrinology (Part C and Part D)
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Utah Pediatric Endocrine Clinic (Part C and Part D)
RECRUITINGSalt Lake City, Utah, 84112, United States
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Vanderbilt University Medical Center (Part C only)
RECRUITINGNashville, Tennessee, 37232, United States
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Worldwide Clinical Trials (Part A and Part B)
COMPLETEDSan Antonio, Texas, 78217, United States
Conditions
Explore the condition pages connected to this study.