New hope for kids with kidney disease: rituximab cuts relapse risk

NCT ID NCT07049172

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether rituximab, a medication that targets certain immune cells, could help children with a challenging form of nephrotic syndrome (a kidney disease) that keeps coming back. 91 children were split into two groups: one received rituximab plus special nursing care, the other received a standard drug (tacrolimus) plus the same care. The goal was to see which approach better prevented relapses and improved quality of life over 6 months.

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Conditions

The condition(s) this trial relates to.

nephrotic syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Wuhan Children's Hospital

    Wuhan, Hubei, 430015, China