New hope for HIV patients with anal cancer: personalized treatment aims to cut recurrence

NCT ID NCT04929028

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 25 times

Summary

This study tests a risk-adapted approach for people with HIV and anal cancer. Low-risk patients receive standard chemotherapy and radiation, while high-risk patients also get the immunotherapy drug nivolumab after standard treatment to help prevent the cancer from coming back. The goal is to see if this approach is safe and effective in controlling the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • George Washington University Medical Center

    Washington D.C., District of Columbia, 20037, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Lyndon Baines Johnson General Hospital

    Houston, Texas, 77026-1967, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Montefiore Medical Center - Moses Campus

    The Bronx, New York, 10467, United States

  • Montefiore Medical Center-Einstein Campus

    The Bronx, New York, 10461, United States

  • Mount Sinai Hospital

    New York, New York, 10029, United States

  • Mount Sinai West

    New York, New York, 10019, United States

  • Pennsylvania Hospital

    Philadelphia, Pennsylvania, 19107, United States

  • University of Illinois

    Chicago, Illinois, 60612, United States

  • Virginia Mason Medical Center

    Seattle, Washington, 98101, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

  • Zuckerberg San Francisco General Hospital

    San Francisco, California, 94110, United States

Conditions

Explore the condition pages connected to this study.