Double treatment hope for SMA babies: gene therapy plus new drug

NCT ID NCT05861986

Summary

This study is testing if adding the drug risdiplam to babies who have already received gene therapy for spinal muscular atrophy (SMA) is safe and helps them improve their movement skills. It involves about 28 children under 2 years old. Researchers will measure changes in the babies' ability to sit, stand, and move over 72 weeks of treatment.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann and Robert H. Lurie Children Hospital of Chicago

    NOT_YET_RECRUITING

    Chicago, Illinois, 60611, United States

  • Charité - Universitätsmedizin Berlin SPZ Abteilung Neuropaediatrie

    RECRUITING

    Berlin, 13353, Germany

  • Children'S Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Healthcare of Atlanta Center for Advanced Pediatrics

    RECRUITING

    Atlanta, Georgia, 30329-2309, United States

  • Children's Hospital of Colorado

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Children's Hospital of the King's Daughter

    RECRUITING

    Norfolk, Virginia, 23510, United States

  • Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

  • Cook Children's Jane and John Justin Neurosciences Center

    RECRUITING

    Fort Worth, Texas, 76104, United States

  • Great Ormond Street Hospital For Children

    RECRUITING

    London, WC1N 3JH, United Kingdom

  • Helen DeVos Children's Hospital at Spectrum Health

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • Instytut Pomnik Centrum Zdrowia Dziecka

    RECRUITING

    Warsaw, 04-730, Poland

  • The University of Texas Southwestern Medical Center at Dallas

    RECRUITING

    Dallas, Texas, 75390, United States

  • UKGM Standort Gießen

    RECRUITING

    Giessen, 35392, Germany

  • University of Arkansas for Medical Sciences

    RECRUITING

    Little Rock, Arkansas, 72103, United States

  • University of Florida Pediatrics

    RECRUITING

    Gainesville, Florida, 32610, United States

  • Uniwersyteckie Centrum Kliniczne

    RECRUITING

    Uniwersyteckie Centrum Kliniczne, 80-952, Poland

Conditions

Explore the condition pages connected to this study.