New hope for recurrent endometrial cancer: Rina-S faces off against standard chemo

NCT ID NCT07166094

Recruiting now Disease control Sponsor: Genmab Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 36 times

Summary

This study compares a new drug called Rina-S to standard chemotherapy (paclitaxel or doxorubicin) in people with endometrial cancer that has returned or worsened after platinum-based chemo and immunotherapy. About 660 participants will be randomly assigned to receive either Rina-S or standard chemo. The goal is to see which treatment better delays cancer growth and extends survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

CH de la Côte Basque
RECRUITING

Bayonne, Pyrénées-Atlantiques, 64109, France
CHU A Coruña
RECRUITING

A Coruña, La Coruña, 15006, Spain
CHU UCL Namur/Ste Elisabeth
RECRUITING

Namur, Wallonia, 5000, Belgium
Calvary Mater Newcastle
RECRUITING

Waratah, New South Wales, 2298, Australia
Cancer Institute Hospital of JFCR
RECRUITING

Tokyo, 135-8550, Japan
Chiba University Hospital- Center for Outpatient
RECRUITING

Chiba, Chiba, 260-8677, Japan
Emory Winship Cancer Inst.
RECRUITING

Atlanta, Georgia, 30308, United States
Emory Winship Cancer Inst.
RECRUITING

Atlanta, Georgia, 30322, United States
Emory Winship Cancer Inst./Emory Decatur Hospital
RECRUITING

Decatur, Georgia, 30033, United States
Fukushima Medical University Hospital
RECRUITING

Fukushima, 960-1247, Japan
Grand Hôpital de Charleroi
RECRUITING

Gilly, Hainaut, 6060, Belgium
Gunma Prefectural Cancer Center
RECRUITING

Ōta, Gunma, 373-8550, Japan
HM Sanchinarro
RECRUITING

Madrid, 28050, Spain
HU Virgen de Valme
RECRUITING

Seville, 41014, Spain
HU Virgen del Rocío
RECRUITING

Seville, 41013, Spain
Haukeland University Hospital
RECRUITING

Bergen, Vestland, NO-5021, Norway
Hyogo Cancer Center
RECRUITING

Hyōgo, 673-0021, Japan
Hôpital Foch
RECRUITING

Suresnes, Île-de-France Region, 92150, France
ICO Angers
RECRUITING

Angers, Pays de la Loire Region, 49055, France
ICZMP
RECRUITING

Lodz, 93-338, Poland
Iwate Medical University Hosp
RECRUITING

Shiwa-gun, Iwate, 028-3695, Japan
Kanagawa Cancer Center
RECRUITING

Yokohama, Kanagawa, 241-8515, Japan
Keio University Hospital
RECRUITING

Tokyo, Tokyo, 160-8582, Japan
Kitasato University Hospital
RECRUITING

Sagamihara-shi, Kanagawa, 252-0373, Japan
Kuopio Univ. Hospital, PSHVA
RECRUITING

Kuopio, Northern Savonia, 70210, Finland
MUHC - Glen Site
RECRUITING

Montreal, Quebec, H4A 3J1, Canada
MedStar Washington Hospital
RECRUITING

Washington D.C., District of Columbia, 20010, United States
Mie University Hospital
RECRUITING

Tsu, Kansai, 514-8507, Japan
NEXT San Antonio
RECRUITING

San Antonio, Texas, 78240, United States
NUC Tohoku Univ. Hospital
RECRUITING

Sendai, Miyagi, 980-8574, Japan
NW Cancer Specs. P.C.
RECRUITING

Happy Valley, Oregon, 97015, United States
National Cancer Center Hospital East
RECRUITING

Chiba, 277-8577, Japan
National Hospital Organization Kyushu Cancer Center
RECRUITING

Fukuoka, 811-1347, Japan
Niigata Cancer Center Hospital
RECRUITING

Niigata, Japan
OUH Radium Hospital
RECRUITING

Oslo, Oslofjord, 0379, Norway
Osaka International Cancer Institute - Osaka - Otemae Acti
RECRUITING

Osaka, Osaka, 541-8567, Japan
Osaka Medical and Pharmaceutical University Hospital
RECRUITING

Takatsuki, 569-8686, Japan
PR Cancer Specialists
RECRUITING

San Juan, 00917, Puerto Rico
SMH - Sarasota - Main Campus
RECRUITING

Sarasota, Florida, 34239, United States
Saitama Medical University - International Medical Center
RECRUITING

Saitama, 350-1298, Japan
Sapporo Medical University Hospital
RECRUITING

Sapporo, 060-8543, Japan
Shizuoka Cancer Center
RECRUITING

Nagaizumi-cho, Shizuoka, 411-8777, Japan
Siedleckie Centrum Onkologii
RECRUITING

Siedlce, Masovian Voivodeship, 08-110, Poland
Sinai Hospital
RECRUITING

Baltimore, Maryland, 21215, United States
TX Onc - Arlington North
RECRUITING

Arlington, Texas, 76012, United States
TX Onc - Bedford
RECRUITING

Bedford, Texas, 76022, United States
TX Onc - Methodist Charlton
RECRUITING

Dallas, Texas, 75237, United States
TX Onc - Methodist Dallas
RECRUITING

Dallas, Texas, 75203, United States
TX Onc - Presbyterian Dallas
RECRUITING

Dallas, Texas, 75231, United States
TX Onc - Sammons
RECRUITING

Dallas, Texas, 75246, United States
Trials365, LLC
RECRUITING

Shreveport, Louisiana, 71103, United States
USOR - Minnesota Oncology
RECRUITING

Minneapolis, Minnesota, 55404, United States
USOR - Minnesota Oncology - Edina Clinic
RECRUITING

Edina, Minnesota, 55435, United States
USOR - Minnesota Oncology-Coon Rapids Clinic
RECRUITING

Coon Rapids, Minnesota, 55433, United States
USOR - Minnesota Oncology-Maplewood Clinic
RECRUITING

Maplewood, Minnesota, 55109, United States
USOR - Minnesota Oncology/ Coon Rapids Clinic
RECRUITING

Coon Rapids, Minnesota, 55433, United States
USOR - Minnesota Oncology/ Maple Grove Clinic
RECRUITING

Maple Grove, Minnesota, 55369, United States
USOR - Minnesota Oncology/ Maplewood Clinic
RECRUITING

Maplewood, Minnesota, 55109, United States
USOR - Minnesota Oncology/ Minneapolis Clinic
RECRUITING

Minneapolis, Minnesota, 55404, United States
USOR - Minnesota Oncology/ Woodbury Clinic
RECRUITING

Woodbury, Minnesota, 55125, United States
USOR - Minnesota Oncology/Edina Clinic
RECRUITING

Edina, Minnesota, 55435, United States
USOR - NW Cancer Specs P.C.
RECRUITING

Portland, Oregon, 97227, United States
USOR - NW Cancer Specs P.C.
RECRUITING

Vancouver, Washington, 98684, United States
USOR - NW Cancer Specs. P.C.
RECRUITING

Tigard, Oregon, 97223, United States
USOR - TX Oncology - SA NE
RECRUITING

San Antonio, Texas, 78217, United States
USOR - Texas Oncology
RECRUITING

Austin, Texas, 78731, United States
USOR - Texas Oncology
RECRUITING

Austin, Texas, 78745, United States
USOR - Texas Oncology
RECRUITING

Harlingen, Texas, 78550, United States
USOR - Texas Oncology
RECRUITING

McAllen, Texas, 78503, United States
USOR - Texas Oncology
RECRUITING

Weslaco, Texas, 78596, United States
USOR - Texas Oncology - Dallas Fort Worth (DFW)
RECRUITING

Fort Worth, Texas, 76104, United States
USOR - Texas Oncology- Austin North
RECRUITING

Austin, Texas, 78758, United States
USOR - Texas Oncology- Horizon Circle
RECRUITING

Waco, Texas, 76712, United States
USOR - Texas Oncology- Waco
RECRUITING

Waco, Texas, 76712, United States
University of Cincinnati Medical Center
RECRUITING

Cincinnati, Ohio, 45219, United States
VITAZ
RECRUITING

Sint-Niklaas, 9100, Belgium
Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States
Willamette Valley Cancer Institute and Research Center - Eugene
RECRUITING

Eugene, Oregon, 97401, United States
William Kahlert Reg. Can. Ctr
RECRUITING

Westminster, Maryland, 21157, United States
Women's Care - 9th Ave
RECRUITING

St. Petersburg, Florida, 33713, United States
Yamagata University Hospital
RECRUITING

Yamagata, 990-9585, Japan

Conditions

Explore the condition pages connected to this study.

ENDOMETRIAL CANCER ENDOMETRIAL CANCER RECURRENT OR PROGRESSIVE ENDOMETRIAL CANCER