New hope for Platinum-Resistant ovarian cancer: Rina-S trial launches

NCT ID NCT07604766

Not yet recruiting Disease control Sponsor: Genmab Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial compares a new drug called Rina-S to standard chemotherapy in 82 people with platinum-resistant ovarian cancer. Participants are randomly assigned to receive either Rina-S or one of four approved chemotherapies. The goal is to see if Rina-S can delay cancer growth better than current treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rinatabart sesutecan (Rina-S)

What this could lead to

If it works, this could offer a new treatment option for people with platinum-resistant ovarian cancer, potentially slowing cancer growth better than current chemotherapies.

What could go wrong

This is an early-stage extension study with only 82 participants, so results may not apply to everyone. Rina-S may not prove more effective than existing chemo and could have side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fallopian tube neoplasm ovarian cancer ovarian carcinoma refractory malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Cancer Hospital

    Beijing, China

  • Chongqing University Cancer Hospital - Chongqing Cancer Hospital

    Chongqing, China

  • Fudan University Shanghai Cancer Hospital

    Shanghai, China

  • Fujian Provincial Cancer Hospital

    Fujian, China

  • Harbin Medical University Cancer Hospital

    Heilongjiang, China

  • Henan Cancer Hospital

    Henan, China

  • Hunan Cancer Hospital

    Hunan, China

  • Liaoning Cancer Hospital

    Liaoning, China

  • Nanjing Drum Tower Hospital (The Affiliated Hospital of Nanjing University Medical School)

    Jiangsu, China

  • Obstetrics & Gynecology Hospital of Fudan University

    Shanghai, China

  • Peking Union Medical College Hospital

    Beijing, China

  • Shandong Cancer Hospital

    Shandong, China

  • Shanxi Cancer Hospital

    Shanxi, China

  • Sun Yat-Sen Memorial Hospital

    Guangdong, China

  • Sun Yat-Sen University Cancer Center

    Guangdong, China

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Shanxi, China

  • The First Hospital of Jilin University

    Jilin City, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjin, China

  • West China Second University Hospital, Sichuan University

    Sichuan, China

  • Zhejiang Cancer Hospital

    Zhejiang, China