New hope for ovarian cancer: Rina-S faces off against chemo in major trial

NCT ID NCT07564141

Not yet recruiting Disease control Sponsor: Genmab Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large Phase 3 trial will test a new drug called Rina-S, alone or with bevacizumab, against standard platinum-based chemotherapy for women with ovarian cancer that has returned after initial treatment. About 688 participants will be randomly assigned to receive either the new drug or standard chemo. The main goal is to see if Rina-S can delay cancer growth better than current treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rina-S (rinatabart sesutecan) with or without bevacizumab

What this could lead to

If successful, this could offer a new treatment option for women with recurrent platinum-sensitive ovarian cancer, potentially improving how long the cancer stays under control.

What could go wrong

This is an early-stage Phase 3 trial, so results are not yet known. The new drug may not work better than standard chemotherapy, and side effects could be similar or different.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fallopian tube cancer ovarian cancer ovarian carcinoma ovarian endometrioid adenocarcinoma ovarian serous adenocarcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••