Liver drug study pulled before it even started

NCT ID NCT04244877

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to see if the antibiotic rifaximin could help people with liver cirrhosis who have a mild form of brain fog called covert hepatic encephalopathy, along with bacterial overgrowth in the gut. Researchers planned to give 40 patients rifaximin for eight weeks and test their thinking skills and gut function. However, the trial was withdrawn before enrolling anyone, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Rifaximin (Xifaxan) tablet

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver hepatic encephalopathy intestinal motility disease small intestinal bacterial overgrowth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.