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Hidden blood mutations linked to heart failure?

NCT ID NCT06626685

Recruiting now Knowledge-focused Sponsor: FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS Source: ClinicalTrials.gov ↗

First seen Jul 10, 2026 · Last updated Jul 10, 2026

Summary

This study investigates whether clonal hematopoiesis of indeterminate potential (CHIP)—a condition where blood cells carry certain mutations—plays a role in heart failure. Researchers will examine 300 adults with acute or chronic heart failure to see how common CHIP is and how it relates to inflammation. The goal is to better understand the biological pathways that worsen heart failure, which could lead to new treatment strategies in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could reveal how blood cell mutations contribute to heart failure, potentially pointing toward new treatment targets.
What could go wrong
This is an observational study, not a treatment trial. It may find no clear link, and results may not lead to direct therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • ATS BERGAMO Agenzia di Tutela della Salute

    ACTIVE_NOT_RECRUITING

    Bergamo, 24121, Italy

  • Asst Papa Giovanni Xxiii - Dip. Di Cardiologia

    RECRUITING

    Bergamo, 24127, Italy

    Contact

    Contact

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