Blood test could end guesswork in rheumatoid arthritis treatment

NCT ID NCT05936970

Ongoing Knowledge-focused Sponsor: Aqtual, Inc. Source: ClinicalTrials.gov ↗

First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time

Summary

This study evaluates a blood test that uses genetic and epigenetic information to help doctors predict which rheumatoid arthritis medication will work best for each patient. Researchers will collect blood samples from 1,410 adults with rheumatoid arthritis who have not responded well to or cannot tolerate previous treatments. The goal is to identify DNA signatures in the blood that can guide personalized treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this blood test could help doctors choose the most effective rheumatoid arthritis treatment for each patient, reducing trial and error.
What could go wrong: This is an observational study, not a treatment trial, so it does not test a new therapy. The test may not prove accurate enough for routine use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RHEUMATOID ARTHRITIS

Contacts and locations

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Locations

AARA Clinical Research/Lone Star Arthritis and Rheumatology

Fort Worth, Texas, 76109, United States
AARA/Kansas City Physician Partners

Kansas City, Missouri, 64151, United States
AARA/Rheumatic Diseases Clinic of Oklahoma

Oklahoma City, Oklahoma, 73102, United States
AARDS Research, Inc

Aventura, Florida, 33180, United States
Accurate Clinical Management

Baytown, Texas, 77521, United States
Accurate Clinical Research

Houston, Texas, 77089, United States
Advanced Rheumatology of Houston

The Woodlands, Texas, 77382, United States
Albuquerque Center for Rheumatology

Albuquerque, New Mexico, 87102, United States
Altoona Center for Clinical Research

Duncansville, Pennsylvania, 16635, United States
Arizona Arthritis & Rheumatology Research

Phoenix, Arizona, 85032, United States
Arnold Arthritis & Rheumatology

Skokie, Illinois, 60076, United States
Arthritis Group Rheumatology

Philadelphia, Pennsylvania, 19152, United States
Arthritis Northwest

Spokane, Washington, 99204, United States
Arthritis Rheumatism and Bone Disease Associates

Voorhees Township, New Jersey, 08043, United States
Arthritis and Osteoporosis Consultants of the Carolinas

Charlotte, North Carolina, 28207, United States
Bay Area Rheumatology

Clearwater, Florida, 33765, United States
Believe Clinical Trials

Coral Springs, Florida, 33065, United States
Cape Fear Arthritis Care

Leland, North Carolina, 28451, United States
Carolina Arthritis Associates

Wilmington, North Carolina, 28401, United States
Carolina Health Specialists/Trial Management Associates

Myrtle Beach, South Carolina, 29572, United States
Clinical Research Institute of Michigan

Saint Clair Shores, Michigan, 48082, United States
GNP Research

Hollywood, Florida, 33024, United States
Highlands Advanced Rheumatology and Arthritis Center (HARAC)

Avon Park, Florida, 33825, United States
Illinois Bone and Joint Institute

Willowbrook, Illinois, 60527, United States
Lake Cumberland Rheumatology

New Albany, Indiana, 47150, United States
Life Clinical Trials

Margate, Florida, 33063, United States
Medvin Clinical Research - Apple Valley

Apple Valley, California, 92307, United States
Medvin Clinical Research - Covina

Covina, California, 91722, United States
Medvin Clinical Research - Riverside

Riverside, California, 92518, United States
Medvin Clinical Research - Tujunga

Tujunga, California, 91042, United States
Medvin Clinical Research - Whittier

Whittier, California, 90602, United States
New England Rheumatology & Osteoporosis

Henniker, New Hampshire, 03242, United States
Overlake Arthritis and Osteoporosis Center

Bellevue, Washington, 98004, United States
PA Regional Center for Arthritis and Osteoporosis Research

Philadelphia, Pennsylvania, 19152, United States
Rheumatology Care Center

Bellaire, Texas, 77401, United States
Sahni Rheumatology & Therapy

West Long Branch, New Jersey, 07764, United States
Shine a Light Research

Sun City Center, Florida, 33573, United States
St. Luke's Clinic

Boise, Idaho, 83712, United States
St. Paul Rheumatology

Eagan, Minnesota, 55121, United States
Triangle Arthritis & Rheumatology

Raleigh, North Carolina, 27612, United States
Vitalia Medical Research

Palm Beach Gardens, Florida, 33410, United States
West Broward Rheumatology Associates

Tamarac, Florida, 33321, United States

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