New pill shows promise for Hard-to-Treat breast cancer

NCT ID NCT05304962

First seen Apr 02, 2026 · Last updated May 16, 2026 · Updated 9 times

Summary

This early-stage study tests a new oral drug, RGT-419B, in people with advanced hormone receptor-positive, HER2-negative breast cancer that has worsened after standard treatments. The goal is to find a safe dose and see if the drug, given alone or with hormone therapy, can help control the disease. About 64 adults with stage III or IV cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hem-Onc Associates of the Treasure Coast

    ACTIVE_NOT_RECRUITING

    Port Saint Lucie, Florida, 34952, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02142, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • New York Cancer and Blood Specialists

    RECRUITING

    Port Jefferson Station, New York, 11776, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University California, Los Angeles

    RECRUITING

    Los Angeles, California, 90404, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California, San Diego

    RECRUITING

    La Jolla, California, 92037, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.