New hope for brain cancer: immune booster and drug combo tested

NCT ID NCT07468136

First seen Mar 18, 2026 · Last updated May 07, 2026 · Updated 8 times

Summary

This study tests two drugs—retifanlimab (an immunotherapy that helps the immune system attack cancer) and DFMO (which slows tumor growth)—in people with progressive high-grade gliomas, aggressive brain tumors. The goal is to find the safest and most effective dose and see if the combination improves the immune response against the tumor. About 33 adults whose tumors are growing despite prior treatment will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.