Weekly shot shows promise for major weight loss in obesity trial

NCT ID NCT07232719

First seen Nov 18, 2025 · Last updated May 16, 2026 · Updated 20 times

Summary

This study tests a once-weekly injection called retatrutide to help people with obesity or overweight lose weight. About 250 adults who do not have type 2 diabetes will receive either the drug or a placebo for 65 weeks. The main goal is to see how much weight they lose and if the treatment is safe.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Albany House Medical Centre

    Wellingborough, NN8 4RW, United Kingdom

  • Artemis Institute for Clinical Research

    Riverside, California, 92503, United States

  • Atlantic Medical

    Penzance, TR18 3DX, United Kingdom

  • Bradford on Avon Health Centre

    Bradford-on-Avon, BA15 1DQ, United Kingdom

  • Care Access - Arlington Heights

    Arlington Heights, Illinois, 60005, United States

  • Care Access - Houston

    Houston, Texas, 77054, United States

  • Care Access - Tamarac

    Tamarac, Florida, 33321, United States

  • Cedar Health Research

    Dallas, Texas, 75251, United States

  • Cedar Health Research - Euless

    Euless, Texas, 76040, United States

  • Cedar Health Research - Fort Worth

    Fort Worth, Texas, 76132, United States

  • Cheadle Community Hospital

    Cheadle, ST10 1NS, United Kingdom

  • Clinical Research Professionals

    Chesterfield, Missouri, 63005, United States

  • Clinvest Headlands Llc

    Springfield, Missouri, 65807, United States

  • FutureMeds - Birmingham

    Birmingham, B21 9RY, United Kingdom

  • FutureMeds - Liverpool

    Bromborough, CH62 6EE, United Kingdom

  • HMC Health Group - Meadows Centre for Health

    Hounslow, TW4 7NR, United Kingdom

  • Headlands Research Orlando

    Orlando, Florida, 32806, United States

  • Headlands Research-El Paso

    El Paso, Texas, 79902, United States

  • IMA Clinical Research Manhattan

    New York, New York, 10036, United States

  • IMA Clinical Research Monroe - Armand

    Monroe, Louisiana, 71201, United States

  • IMA Clinical Research San Antonio

    San Antonio, Texas, 78229, United States

  • IMA Clinical Research Warren

    Warren Township, New Jersey, 07059, United States

  • JEM Research Institute

    Atlantis, Florida, 33462, United States

  • L-MARC Research Center

    Louisville, Kentucky, 40213, United States

  • Layton Medical Centre

    Blackpool, FY3 7EN, United Kingdom

  • Pharmasite Research, Inc.

    Baltimore, Maryland, 21208, United States

  • Rame Group Practice

    Torpoint, PL11 2TB, United Kingdom

  • St Bartholomew's Medical Centre

    Oxford, OX4 1XB, United Kingdom

  • The Adam Practice

    Poole, BH16 5PW, United Kingdom

  • Trial Management Associates - Wilmington - Floral Parkway

    Wilmington, North Carolina, 28403, United States

  • Woodstock Bower Surgery

    Rotherham, S61 1AH, United Kingdom

Conditions

Explore the condition pages connected to this study.