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Arm workouts may boost heart function after spinal cord injury — a trial puts it to the test

NCT ID NCT07725952

Disease control Sponsor: Pusan National University Yangsan Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Sep 04, 2026 · Updated 2 times

Summary

This trial tests whether an 8-week upper-limb resistance training program can improve cardiovascular autonomic function in adults with chronic spinal cord injury. Participants are randomly assigned to either supervised arm exercises three times per week or a control group. Researchers will measure heart rate variability, baroreflex sensitivity, blood pressure changes, and quality of life to see if strength training helps regulate heart function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a supervised upper-limb resistance training program
What this could lead to
If it works, this could point toward a simple exercise program to improve cardiovascular health and reduce dizziness in people with spinal cord injury.
What could go wrong
This is a small, early-stage trial with only 20 participants, so results may not apply widely. The training requires consistent effort, and benefits may vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Provided written informed consent and agreed to participate in the study. * Adults aged 19 to 85 years. * Chronic spinal cord injury (SCI) of traumatic or non-traumatic etiology, at least 6 months after injury. * Cervical or thoracic spinal cord injury. * Classified as American Spinal Injury Association (ASIA) Impairment Scale (AIS) grade A, B, C, or D. * Sufficient upper-limb range of motion to perform resistance training. * Elbow extensor muscle strength of Manual Muscle Test (MMT) grade 3 or higher. Exclusion Criteria: * Presence of any serious medical condition that would preclude participation in the study. * Inability to understand or perform the exercise program. * Uncontrolled diabetes mellitus or progressive neurological disease. * Uncontrolled hypertension (systolic blood pressure \>140 mmHg or diastolic blood pressure \>90 mmHg). * History of cardiovascular disease within the past 6 months. * Current use of medications that may affect heart rate variability (HRV) or baroreflex sensitivity (BRS). * Severe orthostatic hypotension (OH) or autonomic dysreflexia (AD). * Considered unsuitable for participation in the study by a board-certified specialist in Physical and Rehabilitation Medicine.

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Conditions

The condition(s) this trial relates to.

Hypotension, Orthostatic spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal cord injury

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

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  3. A doctor treating you

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Contacts and locations

Locations

  • Pusan National University Yangsan Hospital

    Yangsan, Gyeongsangnam-do, 50612, South Korea

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