Stress relief: could a simple hormone pill ease fatigue for Steroid-Dependent patients?
NCT ID NCT05435781
First seen Mar 27, 2026 · Last updated May 14, 2026 · Updated 7 times
Summary
This study looks at whether taking extra hydrocortisone during times of stress (like illness or emotional strain) can improve fatigue and daily well-being in people whose adrenal glands are underactive due to long-term prednisolone treatment for polymyalgia rheumatica or giant cell arteritis. About 250 adults aged 50 and older who are on a low, stable dose of prednisolone will be randomly assigned to receive either hydrocortisone or a placebo during stressful events. The main goal is to see if this approach helps reduce fatigue and other symptoms.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Phone: •••-•••-•••• Email: •••••@•••••
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Department of Endocrinology, Aarhus University Hospital
RECRUITINGAarhus, Denmark
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Department of Endocrinology, Odense University Hospital
RECRUITINGOdense, Denmark
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Department of Medical Endocrinology, Copenhagen University Hospital, Rigshospitalet
RECRUITINGCopenhagen, 2100, Denmark
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