New hope for kids with tough cancers: drug combo trial launches

NCT ID NCT05004116

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 23 times

Summary

This study is for children and young adults with advanced or metastatic solid tumors that have spread. It tests a new drug called repotrectinib combined with two chemotherapy drugs (irinotecan and temozolomide). The goal is to find the safest dose and see if the combination helps shrink tumors. About 77 participants will take part.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for METASTATIC SOLID TUMOR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.