New drug combo aims to save kidneys in rare cancer patients who skip surgery
NCT ID NCT05656235
First seen Jan 10, 2026 · Last updated May 13, 2026 · Updated 17 times
Summary
This study tests a combination of two cancer drugs, enfortumab vedotin and pembrolizumab, in 20 people with high-grade upper tract urothelial cancer (a rare cancer of the kidney and ureter). Participants are those who cannot or choose not to have standard surgery to remove the kidney. The goal is to see if the drug combo can control the cancer and preserve kidney function, avoiding the need for surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins University: Sibley Memorial Hospital
RECRUITINGWashington D.C., District of Columbia, 20016, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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