5,000-Patient registry tests kidney nerve procedure for Tough-to-Treat high blood pressure

NCT ID NCT01534299

Recruiting now Disease control Sponsor: Medtronic Vascular Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This registry follows 5,000 people with high blood pressure who undergo a procedure called renal denervation. The procedure uses a catheter to deliver radiofrequency energy to nerves in the kidney arteries, which may help lower blood pressure. Participants are tracked for up to 5 years to see how safe and effective the procedure is in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Renal denervation procedure using a catheter that delivers radiofrequency energy to nerves in the kidney arteries
What this could lead to: If successful, this could confirm that renal denervation is a safe and effective long-term option for lowering blood pressure in patients with uncontrolled hypertension.
What could go wrong: This is an observational registry, not a randomized trial, so results may be influenced by patient selection and other factors. The procedure carries risks like artery damage or bleeding, and not all patients may respond.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION

Contacts and locations

Locations

Universitätsklinikum des Saarlandes
RECRUITING

Homburg, Saarlandes, D-66421, Germany
Universitätsspital Basel
RECRUITING

Basel, Switzerland, 4031, Switzerland

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