Major Alzheimer's drug trial aims to slow memory loss

NCT ID NCT06653153

Ongoing Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 study is testing whether the experimental drug remternetug can delay worsening of memory, thinking, and daily function in people with early Alzheimer's disease. About 1,400 participants will receive either remternetug or a placebo for up to 5 years to see which group experiences slower decline. The study focuses on people with very early signs of Alzheimer's who show evidence of amyloid protein in the brain but still have minimal impairment in their daily lives.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

ALPHA Recherche Clinique

Québec, G3K 2P8, Canada
Abbeywell Surgery

Romsey, SO51 7QN, United Kingdom
Acadia Hospital

Bangor, Maine, 04401, United States
Adams Clinical Boston

Boston, Massachusetts, 02116, United States
Adams Clinical Watertown

Watertown, Massachusetts, 02472, United States
Adult Medicine of Lake County, Inc.

Mt. Dora, Florida, 32757, United States
Advanced Memory Research Institute of New Jersey

Toms River, New Jersey, 08755, United States
AdventHealth Orlando

Orlando, Florida, 32804, United States
Ajou University Hospital

Suwon, 16499, South Korea
Alexian Brothers Medical Center

Elk Grove Village, Illinois, 60007, United States
Alpha Recherche Clinique

Québec, G2J 0C4, Canada
Alpha Recherche Clinique - Lévis

Lévis, G6V 0C9, Canada
Alpine Clinical Research Center

Boulder, Colorado, 80301, United States
Alzheimer's Research and Treatment Center

Stuart, Florida, 34997, United States
Alzheimer's Research and Treatment Center

Wellington, Florida, 33414, United States
Anhui Provincial Hospital

Hefei, 230036, China
Aqualane Clinical Research

Naples, Florida, 34105, United States
Artemis Institute for Clinical Research

San Diego, California, 92103, United States
Asan Medical Center

Seoul, 05505, South Korea
Austin Health

Ivanhoe, 3079, Australia
Axiom Brain Health LLC

Tampa, Florida, 33609, United States
Banner Alzheimer's Institute

Phoenix, Arizona, 85006, United States
Banner Alzheimer's Institute Tucson

Tucson, Arizona, 85718, United States
Barcelonabeta Brain Research Center

Barcelona, 08005, Spain
Baycrest Health Sciences

Toronto, M6A 2E1, Canada
Beijing Anding Hospital - Affiliated Capital University of Medical Science

Beijing, 100088, China
Beijing Tiantan Hospital Affiliated to Capital Medical University

Beijing, 100071, China
Bluewater Clinical Research Group Inc.

Sarnia, N7T 4X3, Canada
Boocs Clinic Fukuoka

Fukuoka, 812-0025, Japan
Boston Center for Memory

Newton, Massachusetts, 02459, United States
Boston Clinical Trials

Boston, Massachusetts, 02131, United States
Box Hill Hospital

Box Hill, 3128, Australia
Bradenton Research Center, Inc.

Bradenton, Florida, 34205, United States
Brain Matters Research

Delray Beach, Florida, 33445, United States
Butler Hospital

Providence, Rhode Island, 02906, United States
California Neuroscience Research, LLC

Sherman Oaks, California, 91403, United States
Care Access - 801 South Power Road, Mesa

Mesa, Arizona, 85206, United States
Care Access - Arlington 2

Arlington, Virginia, 22206, United States
Care Access - Arlington Heights

Arlington Heights, Illinois, 60005, United States
Care Access - Aurora

Aurora, Colorado, 80012, United States
Care Access - Baltimore

Baltimore, Maryland, 21213, United States
Care Access - Charlotte

Charlotte, North Carolina, 28210, United States
Care Access - Decatur

Decatur, Georgia, 30030, United States
Care Access - Georgetown

Georgetown, Texas, 78633, United States
Care Access - Hoboken

Hoboken, New Jersey, 07030, United States
Care Access - Houston

Houston, Texas, 77054, United States
Care Access - Huntington Beach

Huntington Beach, California, 92648, United States
Care Access - Lake Charles (Bayou Pines)

Lake Charles, Louisiana, 70601, United States
Care Access - Lima

Lima, Ohio, 45805, United States
Care Access - Quincy

Quincy, Massachusetts, 02169, United States
Care Access - South Indianapolis

Indianapolis, Indiana, 46227, United States
Care Access - Tampa

Tampa, Florida, 33625, United States
Caribbean Medical Research Center

San Juan, 00918, Puerto Rico
Cedar Valley Medical Specialists

Waterloo, Iowa, 50701, United States
CenExel Rocky Mountain Clinical Research

Englewood, Colorado, 80113, United States
Center for Advanced Research & Education

Gainesville, Georgia, 30501, United States
Central Texas Neurology Consultants, PA

Round Rock, Texas, 78681, United States
Chang Gung Medical Foundation-Linkou Branch

Taoyuan District, 333, Taiwan
Chang Gung Memorial Hospital at Kaohsiung

Kaohsiung Niao Sung Dist, 83301, Taiwan
Changhua Christian Hospital

Changhua County, 50006, Taiwan
Charter Research - Lady Lake

The Villages, Florida, 32162, United States
Charter Research - Winter Park

Orlando, Florida, 32803, United States
China Medical University Hospital

Taichung, 404332, Taiwan
Chonnam National University Hospital

Gwangju, 61469, South Korea
Chungbuk National University Hospital

Cheongju-si, 28644, South Korea
Citizens Memorial Hospital District

Bolivar, Missouri, 65613, United States
ClinCloud

Maitland, Florida, 32751, United States
ClinCloud

Melbourne, Florida, 32940, United States
Clinical Research Hospital Tokyo

Shinjuku-ku, 160-0004, Japan
Clinical Research Professionals

Chesterfield, Missouri, 63005, United States
Clinical Research of Philadelphia

Philadelphia, Pennsylvania, 19114, United States
Clinical Trials Research

Sacramento, California, 95821, United States
Clinique Mémoire de Montréal

Montreal, H3G 1H9, Canada
Columbus Memory Center, LLC

Columbus, Georgia, 31909, United States
Conquest Research

Winter Park, Florida, 32789, United States
Consano Clinical Research, LLC

Shavano Park, Texas, 78231, United States
Cotton O'Neil Clinical Research Center

Topeka, Kansas, 66606, United States
Diex Recherche Inc. Division Victoriaville

Victoriaville, G6P 3Z8, Canada
Eastern Virginia Medical School (EVMS) Medical Group

Norfolk, Virginia, 23510, United States
Ecogene-21 - Cmas

Chicoutimi, G7H 0S7, Canada
El Faro Health and Therapeutics

Rio Grande City, Texas, 78582, United States
Emerald Coast Neurology - Airport Boulevard

Pensacola, Florida, 32504, United States
Emeritus Research

Botany, 2019, Australia
Emeritus Research

Camberwell, 3124, Australia
Ewha Womans University Seoul Hospital

Gangseo-gu, 07804, South Korea
Fukuwa Clinic

Chūōku, 104-0031, Japan
Fundació ACE

Barcelona, 08028, Spain
Fusion Clinical Research

Norwood, 5067, Australia
Gachon University Gil Medical Center

Namdong-gu, 21565, South Korea
Gadolin Research

Beaumont, Texas, 77702, United States
Gangnam Severance Hospital, Yonsei University Health System

Gangnam-gu, 06273, South Korea
Genesis Neuroscience Clinic

Knoxville, Tennessee, 37909, United States
GenesisCare - Maitland

East Maitland, 2323, Australia
Genge Partners

Montreal, H4A 3T2, Canada
Great Lakes Clinical Trials - Andersonville

Chicago, Illinois, 60640, United States
Guangdong Provincial People's Hospital

Guangzhou, 510080, China
Guangzhou First People's Hospital

Guangzhou, 510180, China
Guangzhou Medical University 2nd Hospital

Guangzhou, 510260, China
HammondCare

Malvern, 3144, Australia
Hanyang University Seoul Hospital

Seoul, 04763, South Korea
HealthPartners Neuroscience Center

Saint Paul, Minnesota, 55130, United States
Healthy Brain Clinic

Long Beach, California, 90804, United States
Heishinkai Medical Group ToCROM Clinic

Shinjuku-ku, 160-0008, Japan
Higashi Shinjuku Clinic

Shinjuku-ku, 169-0072, Japan
Homecroft Surgery

Redruth, TR16 4ET, United Kingdom
Hospital Clínic de Barcelona

Barcelona, 08036, Spain
Hospital Universitario Quironsalud Madrid

Pozuelo de Alarcón, 28223, Spain
Hospital Victoria Eugenia

Seville, 41009, Spain
Hospital de la Santa Creu i Sant Pau

Barcelona, 08041, Spain
Huashan Hospital, Fudan University

Shanghai, 200040, China
Hyogo Prefectural Harima-Himeji General Medical Center

Himeji, 670-8560, Japan
IMA Clinical Research

Albuquerque, New Mexico, 87109, United States
IMA Clinical Research San Antonio

San Antonio, Texas, 78229, United States
INSPIRA Clinical Research

San Juan, 00918, Puerto Rico
Indago Research & Health Center, Inc

Hialeah, Florida, 33012, United States
Inglewood Clinical

Inglewood, California, 90301, United States
Inha University Hospital

Incheon, 22332, South Korea
Instituto De Neurologia Dra. Ivonne Fraga

San Juan, 00918, Puerto Rico
Invicro

New Haven, Connecticut, 06510, United States
Ipswich Hospital

Ipswich, 4305, Australia
Irvine Clinical Research

Irvine, California, 92614, United States
Iwata Neurosurgery Clinic

Osaka, 536-0007, Japan
JEM Research Institute

Atlantis, Florida, 33462, United States
Jeju National University Hospital

Jeju City, 63241, South Korea
Jinan Central Hospital

Jinan, 250013, China
Josephson Wallack Munshower Neurology, PC

Indianapolis, Indiana, 46256, United States
K2 MEDICAL Research THE VILLAGES

Lady Lake, Florida, 32159, United States
K2 Medical Research ORLANDO

Maitland, Florida, 32751, United States
K2 Medical Research WINTER GARDEN

Clermont, Florida, 34711, United States
KARA Institute for Neurological Diseases

Macquarie Park, 2113, Australia
Kanto Central Hospital

Setagaya-ku, 158-8531, Japan
Kawartha Centre - Redefining Healthy Aging

Peterborough, K9H 2P4, Canada
Kawashima Neurology Clinic

Fujisawa, 251-0038, Japan
Kerwin Medical Center

Dallas, Texas, 75231, United States
Kerwin Medical Center - Oak Cliff

Dallas, Texas, 75216, United States
Keystone Clinical Studies

Plymouth Meeting, Pennsylvania, 19462, United States
Ki Health Partners, LLc, dba New England Institute for Clinical Research

Stamford, Connecticut, 06905, United States
Kobe University Hospital

Kobe, 650-0017, Japan
Konkuk University Medical Center

Seoul, 05030, South Korea
Layton Medical Centre

Blackpool, FY3 7EN, United Kingdom
MD First Research - Chandler

Chandler, Arizona, 85286, United States
Marine Lake Medical Practice

West Kirby, CH48 5AA, United Kingdom
MedVadis Research Corporation

Waltham, Massachusetts, 02451, United States
Medical Corporation Chiseikai Tokyo Center Clinic

Chūōku, 103-0027, Japan
Medical Corporation Heishinkai OCROM Clinic

Suita-shi, 565-0853, Japan
Medication Management

Greensboro, North Carolina, 27405, United States
Merritt Island Medical Research, LLC

Merritt Island, Florida, 32952, United States
MoCA Research and Innovation Inc.

Greenfield Park, J4V 2J2, Canada
Monroe Biomedical Research

Monroe, North Carolina, 28112, United States
Moorgreen Hospital

Southampton, SO30 3JB, United Kingdom
Mountain Neurological Research Center

Basalt, Colorado, 81621, United States
NIHR Manchester Clinical Research Facility

Manchester, M13 9WL, United Kingdom
Nanjing Brain Hospital

Nanjing, 210029, China
National Center for Geriatrics and Gerontology

Ōbu, 474-8511, Japan
National Taiwan University Hospital

Taipei, 10002, Taiwan
National Taiwan University Hospital Yun-Lin Branch Dou-Liou Region

Douliu, 640, Taiwan
Neuro-Pain Medical Center

Fresno, California, 93710, United States
NeuroClin

Motherwell, ML1 4UF, United Kingdom
Neurology Clinic, P.C.

Cordova, Tennessee, 38018, United States
Neuropsychiatric Research Center of Southwest Florida

Fort Myers, Florida, 33912, United States
New Age Medical Research Corporation

Miami, Florida, 33186, United States
New Taipei Municipal TuCheng Hospital

New Taipei City, 236, Taiwan
Next Level Urgent Care

Houston, Texas, 77057, United States
North Georgia Clinical Research

Woodstock, Georgia, 30189, United States
North Star Medical Research

Middleburg Heights, Ohio, 44130, United States
Northwest Clinical Research Center

Bellevue, Washington, 98007, United States
Northwest Clinical Trials

Boise, Idaho, 83704, United States
OCT Research ULC

Kelowna, V1Y 1Z9, Canada
Ottawa Memory Clinic

Ottawa, K1Z 1G3, Canada
P-One Clinic

Hachiōji, 192-0071, Japan
Palm Beach Neurology

West Palm Beach, Florida, 33407, United States
Palmetto Clinical Research

Summerville, South Carolina, 29485, United States
Parkway Medical Center

Birmingham, Alabama, 35215, United States
Policlinica Gipuzkoa

San Sebastián, 20014, Spain
Private Practice - Dr. Ronald Louis Schwartz

Hattiesburg, Mississippi, 39401, United States
Progressive Medical Research

Port Orange, Florida, 32127, United States
Providence Medical Foundation

Santa Rosa, California, 95403, United States
Pudong New Area People's Hospital Shanghai

Shanghai, 201200, China
Pusan National University Hospital

Busan, 49241, South Korea
Q&T Research Sherbrooke Inc.

Sherbrooke, J1J 2G2, Canada
QUEST Research Institute

Farmington Hills, Michigan, 48334, United States
Rainier Clinical Research Center

Renton, Washington, 98057, United States
Ray Dolby Brain Health Center

San Francisco, California, 94114, United States
Re:Cognition Health

Fairfax, Virginia, 22031, United States
Re:Cognition Health - Birmingham

Birmingham, B16 8LT, United Kingdom
Re:Cognition Health - Chicago

Chicago, Illinois, 60611, United States
ReMind UK

Bath, BA1 3NG, United Kingdom
Renji Hospital Shanghai Jiao Tong University School of Medicine

Shanghai, 200135, China
Renstar Medical Research

Ocala, Florida, 34470, United States
Revival Research Institute, LLC

Dearborn, Michigan, 48126, United States
Rhode Island Mood & Memory Research Institute

East Providence, Rhode Island, 02914, United States
Riverside Clinical

Riverside, California, 92506, United States
Roborough Surgery

Plymouth, PL6 6PH, United Kingdom
SCB Research Center

Bayamón, 00961, Puerto Rico
Saiseikai Imabari Hospital

Imabari, 799-1592, Japan
Sakurazaka Clinic SophyAnce

Minatoku, 106-0032, Japan
Samoncho Clinic

Shinjuku, 160-0017, Japan
Samsung Medical Center

Seoul, 06351, South Korea
Scottish Brain Sciences

Edinburgh, EH12 5PJ, United Kingdom
Senior Adults Specialty Research

Austin, Texas, 78757, United States
Seoul National University Bundang Hospital

Seongnam, 13620, South Korea
Seoul National University Hospital

Seoul, 03080, South Korea
Shaanxi provincial people's hospital

Xi'an, 710068, China
Shanghai Sixth People's Hospital

Shanghai, 200030, China
Sharp Neurocognitive Research Center

San Diego, California, 92123, United States
Showa General Hospital

Kodaira, 187-8510, Japan
Sichuan Provincial People's Hospital

Chengdu, 610072, China
Sir Run Run Hospital of Nanjing Medical University

Nanjing, 211166, China
Southern Neurology

Kogarah, 2217, Australia
St Pancras Clinical Research

London, EC2Y 8EA, United Kingdom
St Vincent's Hospital

Sydney, 2010, Australia
Stedman Clinical Trials

Tampa, Florida, 33613, United States
Summit Headlands

Portland, Oregon, 97210, United States
Suncoast Clinical Research, Inc.

New Port Richey, Florida, 34652, United States
Sunnybrook Research Institute

Toronto, M4N 3M5, Canada
Syrentis Clinical Research

Santa Ana, California, 92705, United States
Tachikawa Hospital

Tachikawa, 190-8531, Japan
Taichung Veterans General Hospital

Taichung, 407, Taiwan
Taipei Medical University Shuang Ho Hospital

New Taipei City, 235, Taiwan
Taipei Veterans General Hospital

Taipei, 11217, Taiwan
Takatsuki Hospital

Takatsuki-shi, 569-1192, Japan
Tandem Clinical Research

Marrero, Louisiana, 70072, United States
Tatsuoka Neurology Clinic

Kyoto, 600-8811, Japan
TecTum Research

Davie, Florida, 33024, United States
The Affiliated Hospital of Xuzhou Medical College

Xuzhou, 221006, China
The Catholic Univ. of Korea Seoul St. Mary's Hospital

Seoul, 06591, South Korea
The Cognitive and Research Center of New Jersey

Springfield, New Jersey, 07081, United States
The Cognitive and Research Center of New Jersey - Ridgewood

Ridgewood, New Jersey, 07450, United States
The First Affiliated Hospital of Henan University of Science &Technology

Luoyang, 471003, China
The First Affiliated Hospital of Nanchang University

Nanchang, 330006, China
The First Affiliated Hospital of Xi'an Medical University

Xi'an, 710077, China
The First Hospital of Hebei Medical University

Shijiazhuang, 050031, China
The First Hospital of Jilin University

Changchun, 100012, China
The Medical Arts Health Research Group - West Vancouver

West Vancouver, V7T 1C5, Canada
The Neuron Clinic - San Marcos

San Marcos, California, 92069, United States
The Queen Elizabeth Hospital

Woodville, 5011, Australia
The Royal Melbourne Hospital

Parkville, 3050, Australia
The Second Affiliated Hospital of Nanchang University

Nanchang, 330000, China
The Second Affiliated Hospital of Soochow University

Suzhou, 215004, China
The University of Queensland

Herston, 4029, Australia
The University of Texas Health Science Center at Houston

Houston, Texas, 77054, United States
The University of Tokyo Hospital

Bunkyō City, 113-8655, Japan
Tianjin Medical University General Hospital

Tianjin, 300052, China
Tokyo Asbo Clinic

Chūōku, 104-0031, Japan
Tokyo Metropolitan Geriatric Hospital

tabashi City, 173-0015, Japan
Tokyo-Eki Center-building Clinic

Chūōku, 103-0027, Japan
Toronto Memory Program

Toronto, M3B 2S7, Canada
Tribe Clinical Research, LLC- Greenville

Greenville, South Carolina, 29607, United States
UNB Sumiyoshi Jinjamae Clinic

Fukuoka, 812-0018, Japan
USC Clinical Trials Brisbane (South Bank)

South Brisbane, 4101, Australia
USC Clinical Trials Sunshine Coast

Birtinya, 4575, Australia
University Of Nebraska Medical Center

Omaha, Nebraska, 68198, United States
VIN - Aventura

Aventura, Florida, 33180, United States
VIN-Andrew Lerman

Miami, Florida, 33133, United States
Vector Clinical Trials

Las Vegas, Nevada, 89128, United States
Wako Hospital

Wako, 351-0111, Japan
Wonju Severance Christian Hospital

Wŏnju, 26426, South Korea
Xiangya Hospital Central South University

Changsha, 410008, China
Xianyang Hospital of Yan'an University

Xianyang, 712000, China
Xuzhou Central Hospital

Xuzhou, 221018, China
Zhujiang Hospital

Guangzhou, 510280, China
Zigong First People's Hospital

Zigong, 643000, China

Conditions

Explore the condition pages connected to this study.

ALZHEIMER S DISEASE