Simple blood tests from home may predict dementia risk

NCT ID NCT04516499

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 36 times

Summary

This study looks at a protein called neurofilament light chain in the blood of people who may develop frontotemporal dementia due to family genes. Researchers want to see if levels of this protein change over time and can be measured reliably from blood samples collected at home. The goal is to better understand the disease and find ways to track it without frequent clinic visits.

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Contacts and locations

Locations

  • Columbia University

    New York, New York, 10032, United States

  • Johns Hopkins University School of Medicine

    Baltimore, Maryland, 21287, United States

  • Massachusetts General Hospital

    Charlestown, Massachusetts, 02129, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • University of California, San Francisco

    San Francisco, California, 94158, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.