New drug combo aims to prevent oxygen drops during lung scope procedures

NCT ID NCT07395596

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding remimazolam to standard sedation (propofol and alfentanil) can lower the risk of low oxygen levels in high-risk patients during painless tracheoscopy. About 360 participants with serious health conditions (ASA class 3-4) will be randomly assigned to one of two drug regimens. The goal is to find a safer way to sedate patients while keeping them comfortable and reducing complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

remimazolam combined with propofol and alfentanil

What this could lead to

If it works, this could offer a safer sedation option for high-risk patients needing bronchoscopy, reducing dangerous drops in oxygen levels.

What could go wrong

This is a Phase 4 trial, but it's still early and results may not apply to all patients. Risks include allergic reactions or unexpected side effects from the drug combination.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Hypoxia lymphangiectasis pulmonary tuberculosis respiratory tract infectious disorder trachea neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shaoxing City First People's Hospital

    NOT_YET_RECRUITING

    Shaoxing, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affliated Hospital, Zhejiang University School Of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••