New drug combo aims to prevent oxygen drops during lung scope procedures

NCT ID NCT07395596

Recruiting now Symptom relief Sponsor: First Affiliated Hospital of Zhejiang University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding remimazolam to standard sedation (propofol and alfentanil) can lower the risk of low oxygen levels in high-risk patients during painless tracheoscopy. About 360 participants with serious health conditions (ASA class 3-4) will be randomly assigned to one of two drug regimens. The goal is to find a safer way to sedate patients while keeping them comfortable and reducing complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remimazolam combined with propofol and alfentanil
What this could lead to: If it works, this could offer a safer sedation option for high-risk patients needing bronchoscopy, reducing dangerous drops in oxygen levels.
What could go wrong: This is a Phase 4 trial, but it's still early and results may not apply to all patients. Risks include allergic reactions or unexpected side effects from the drug combination.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Hypoxia lymphangiectasis pulmonary tuberculosis respiratory tract infectious disorder trachea neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOTRACHEAL TUMOUR LYMPHADENECTASIS PHTHISIS PULMONARY INFECTION PULMONARY NODULE

Contacts and locations

Locations

Shaoxing City First People's Hospital
NOT_YET_RECRUITING

Shaoxing, Zhejiang, 310000, China
The First Affliated Hospital, Zhejiang University School Of Medicine
RECRUITING

Hangzhou, Zhejiang, 310000, China

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