Robot and 3D imaging join forces to spot lung cancer in HIV patients

NCT ID NCT07663656

Not yet recruiting Diagnosis Sponsor: wu qingguo Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new robotic bronchoscopy system that uses real-time 3D imaging to help doctors biopsy lung nodules in people with HIV. The goal is to see if this robot-guided approach is more accurate and safer than current navigation methods. One hundred participants will be randomly assigned to either the robot or a standard electromagnetic navigation system. If the biopsy shows cancer and it is safe, doctors may also treat the nodule with freezing (cryoablation) during the same procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Robotic bronchoscopy with CBCT-guided multimodal image fusion and targeted cryobiopsy
What this could lead to: If successful, this could provide a more accurate and safer way to diagnose lung nodules in people with HIV, potentially allowing same-session treatment for early-stage lung cancer.
What could go wrong: This is an early-stage study with only 100 participants, so results may not apply to everyone. The robotic system is complex and may not always reach the nodule, requiring alternative procedures.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV INFECTIONS PULMONARY NODULE

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