Tiny heart implant aims to ease strain in rare lung disease
NCT ID NCT03838445
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early study tests a small, permanent device called the V-Wave Interatrial Shunt in 9 people with severe pulmonary arterial hypertension (PAH). The device is placed in the heart during a minimally invasive procedure to create a small opening between the upper chambers, which may help relieve pressure on the right side of the heart. The main goals are to check safety and see if the device works as intended.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- V-Wave Interatrial Shunt (a permanent implant placed in the heart to create a small passage between upper chambers)
- What this could lead to
- If it works, this device could offer a new way to reduce strain on the right side of the heart and improve daily function for people with severe pulmonary arterial hypertension.
- What could go wrong
- This is a very early, first-in-human trial with only 9 participants. The device is permanent and carries risks like heart or blood vessel complications. Success in this small group may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Instituto Nacional de Cardiologia
Mexico City, Mexico
-
Keck Medical Center of USC
Los Angeles, California, 90033, United States
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University of California, San Francisco
San Francisco, California, 94143, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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