New hope for rare GIST mutations: regorafenib study targets stubborn tumors
NCT ID NCT06087263
First seen Jan 21, 2026 · Last updated May 14, 2026 · Updated 20 times
Summary
This study tests if the drug regorafenib can help control gastrointestinal stromal tumors (GIST) that have specific gene mutations (KIT exon 17, 18, or 14, or SDHB deficiency) after imatinib has stopped working. It includes adults with measurable, unresectable tumors. The main goal is to check safety and how well the drug controls the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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